منابع مشابه
Epigenetic Drugs for Multiple Sclerosis
There is increasing evidence that abnormalities in epigenetic mechanisms of gene expression contribute to the development of multiple sclerosis (MS). Advances in epigenetics have given rise to a new class of drugs, epigenetic drugs. Although many classes of epigenetic drugs are being investigated, at present most attention is being paid to two classes of epigenetic drugs: drugs that inhibit DNA...
متن کاملThe function of epigenetic processes in multiple sclerosis: review article
Multiple Sclerosis (MS) is a chronic neurological and inflammatory disorder that affects the nervous system. The etiology of MS is unknown, but genetic and environmental factors are involved in its pathogenesis. There is increasing evidence suggesting the role of epigenetic mechanisms in the pathogenesis of multiple sclerosis. Lack of vitamin D, smoking, and Epstein barr virus can cause epigene...
متن کاملEpigenetic mechanisms in pathogenesis of multiple sclerosis
Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system with immune induced myelin destruction followed by multifocal demyelination of the nervous tissues.1 MS is the most widely spread among the human diseases characterized by myelin destruction .2 Until now both the etiology and pathogenesis of MS have to a large extent remained unclear. Substantial efforts have ...
متن کاملDisease-modifying drugs for relapsing-remitting multiple sclerosis and future directions for multiple sclerosis therapeutics.
With the development of effective therapies for multiple sclerosis (MS), therapeutic nihilism, which was so prevalent just 10 years ago, has given way to exuberance and optimism. The current mood is understandable because MS is such a devastating disease. Within 10 years of symptom onset, 50% of patients with MS are unable to carry out household and employment responsibilities; within 15 to 20 ...
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ژورنال
عنوان ژورنال: Current Neuropharmacology
سال: 2016
ISSN: 1570-159X
DOI: 10.2174/1570159x13666150211001600